Whitehead Institute scientists have determined how to use alpaca-derived, single-domain antibody fragments (also called VHHs or nanobodies) to perturb cellular processes in mammalian cells, including the infection of human cells by influenza A virus (IAV) and vesicular stomatitis virus (VSV). With improved knowledge of protein activity, scientists can tease apart the roles individual proteins play in cellular pathways, understand how … Read More
