Whitehead Institute scientists have determined how to use alpaca-derived, single-domain antibody fragments (also called VHHs or nanobodies) to perturb cellular processes in mammalian cells, including the infection of human cells by influenza A virus (IAV) and vesicular stomatitis virus (VSV). With improved knowledge of protein activity, scientists can tease apart the roles individual proteins play in cellular pathways, understand how … Read More
Crisis over syphilis treatment as Canada running out of drug used to treat potentially deadly infection
With syphilis spreading in Canada at rates unseen in decades, doctors are struggling to cope with a shortage of the main drug used to treat the potentially deadly infection. The Public Health Agency of Canada took the rare step recently of posting guidelines on how to ration Bicillin, and what alternative medications might be appropriate in some cases. It’s the … Read More